Tuesday, August 9, 2011
Antibioctic-resistant?
There are a few ways that bacteria can become resistant. Bacteria can spontaneously mutate to become resistant to certain drugs. These bacteria survive and p on their resistance genes to offspring. After a while all the bacteria will be resistant to the same drug which is very bad! Also bacteria can recombine information by conjugation (bacteria ) or "mating". Pretty much if a bacteria has a segment of their dna, on a plasmid, that is resistant to a drug, they can p it on to another bacteria by transferring a segment of their dna into another bacteria, then that segment of the bacteria becomes incorporated into the other bacterium's dna. And they become resistant. Multi resistant bacteria can evolve if you use multiple antibiotics at once. The bacteria that survive will be resistant to a multiple number of drugs and will p on their genes and then you will have a bunch of bacteria that are all resistant to multiple drugs! Yikes! Sometimes you can "solve" this problem by first exposing bacteria to a drug and letting the bacteria become resistant overtime. Then stop taking the drug. The new environment will favor the "wild type" or the bacteria that got killed off when you first introduced the drug. These wild type are more likely to not have any resistance. If you expose these wild type to multiple antibiotics then you have a really good chance of wiping them out.
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